I’d shut it off first. Less chance of snagging yourself in the fan. The bolts should take a 9/16” wrench.
Yes, the front bolts are 7/16 not 3/8. depending on the manifold used there may not be a lot of clearance for a wrench or socket. If a thin wall socket cannot be found maybe grinding one down to make it thinner would help. I put a different manifold on my '50 and there wasn't enough clearance to tighten it up. I used a longer bolt with a sleeve on it to make things easier.